Metabolic Pathway Alterations that Support Cell Proliferation
نویسندگان
چکیده
منابع مشابه
Metabolic pathway alterations that support cell proliferation.
Proliferating cells adapt metabolism to support the conversion of available nutrients into biomass. How cell metabolism is regulated to balance the production of ATP, metabolite building blocks, and reducing equivalents remains uncertain. Proliferative metabolism often involves an increased rate of glycolysis. A key regulated step in glycolysis is catalyzed by pyruvate kinase to convert phospho...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Symposia on Quantitative Biology
سال: 2011
ISSN: 0091-7451,1943-4456
DOI: 10.1101/sqb.2012.76.010900